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Analysis of the sputum and inflammatory alterations of the airways in patients with common variable immunodeficiency and bronchiectasis
(Faculdade de Medicina / USP, 2009)
INTRODUCTION: Common variable immunodeficiency is characterized by defective antibody production and recurrent pulmonary infections. Intravenous immunoglobulin is the treatment of choice, but the effects of Intravenous ...
Interactive effects of mechanical ventilation, inhaled nitric oxide and oxidative stress in acute lung injury
(Elsevier B.V., 2014-01-01)
To compare conventional mechanical ventilation (CMV) and high-frequency oscillatory ventilation (HFOV), with/without inhaled nitric oxide (iNO), for oxygenation, inflammation, antioxidant/oxidative stress status, and DNA ...
Granulocyte-targeted therapies for airway diseases
The average respiration rate for an adult is 12–20 breaths per minute, which constantly exposes the lungs to
allergens and harmful particles. As a result, respiratory diseases, which includes asthma, chronic obstructive ...
Effects of Melatonin on the Defense to Acute Hypoxia in Newborn Lambs
(2019)
Neonatal lambs, as other neonates, have physiologically a very low plasma melatonin concentration throughout 24 h. Previously, we found that melatonin given to neonates daily for 5 days decreased heart weight and changed ...
Protective phenotypes of club cells and alveolar macrophages are favored as part of endotoxin-mediated prevention of asthma
(Soc Experimental Biology Medicine, 2014-12)
Atopic asthma is a chronic allergic disease that involves T-helper type 2 (Th2)-inflammation and airway remodeling. Bronchiolar club cells (CC) and alveolar macrophages (AM) are sentinel cells of airway barrier against ...
Mucociliary Clearance of Different Respiratory Conditions: A Clinical Study
(Georg Thieme Verlag Kg, 2021-01-01)
Introduction Mucociliary clearance (MCC) is the first line of defense of the pulmonary system. Mucociliary clearance impairment may lead to increased risk of respiratory infections, lung injury, pulmonary repair problems, ...
Dispositivo mecânico que promove insuflação e exsuflação pulmonar
(Universidade Federal de Minas GeraisUFMG, 2008-07-01)
The cough is an important means of pulmonary defense as we are led to pathological situations, with progressive accumulation of secretion in the tracheobronchial tree. Patients with neuromuscular pathologies are prone to ...